Figure 2 | Scientific Reports

Figure 2

From: Silencing an insulin-induced lncRNA, LncASIR, impairs the transcriptional response to insulin signalling in adipocytes

Figure 2

UCSC browser image of LncASIR and super-enhancer epigenetic signature at lncASIR loci. (A) RNA-seq data from subcutaneous fat and (B) from epididymal fat from adipose tissue lncRNA catalog by Alvarez et al. have been mapped onto UCSC browser. (C) Gene structure annotation based on Refseq. (D–F) ENCODE ChIP-seq signal from H3K4me1, H3K4me3, and H3K27ac marks in brown adipose tissue as density of processed signal enrichment. (G) PPARγ binding site from ChIP-seq data. (H) Abundance of super enhancer lncRNAs versus non-super enhancer lncRNAs. (I) Genomic region enrichment annotation tool result for super enhancer lncRNAs. Graphs have been drawn using Prism 8. While UCSC browser image is generated using UCSC and labels edited using Adobe Illustrator.

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