Figure 5 | Scientific Reports

Figure 5

From: The effect of exogenous melatonin on reducing scoliotic curvature and improving bone quality in melatonin-deficient C57BL/6J mice

Figure 5

Representative in vivo CT images of the fifth lumbar vertebra in each group. (A) Bipedal mouse (n = 20), (B) bipedal mouse with melatonin treatment (n = 18), (C) quadrupedal mouse (n = 20) and (D) quadrupedal mouse with melatonin treatment (n = 19). The cancellous bone from bipedal mouse (A) and quadrupedal mouse (C) without melatonin treatmentshowed rod-like trabeculae with disconnected irregular surfaces, while cancellous bone frombipedal mouse and quadrupedal mousetreated with melatonin (B,D) had plate-like trabeculae that were markedly increased, thickened and interconnected.

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