Figure 8
Effects of CoQ10 during Tac-induced mitochondrial ROS production in INS-1 cells. (a,b) MitoSOX Red staining to detect mitochondrial superoxide anion (O2−) levels by flow cytometric analysis. (c) Representative time-lapse images of cells treated for 12 h with MitoSOX Red in the presence or absence of Tac and CoQ10 were taken from the same field. Scale bar = 1000 µm (all panels). Data are presented as the mean ± SE (n = 5). One-way ANOVA was used to analyze the data. &P < 0.05 versus the control group; $P < 0.05 versus the CoQ10 groups; #P < 0.05 versus the Tac group.
