Figure 2

RAGE inhibition improves arterial oxygenation after acid-induced lung injury. Arterial oxygen tension (PaO2)/inspiratory oxygen fraction (FiO2) in uninjured (Sham), acid-injured (HCl) and acid-injured piglets treated with RAGE antagonist peptide (HCl + RAP) or recombinant sRAGE (HCl + sRAGE) (n = 12 per group at each time point). Individual values are reported. Time × group interaction and post-hoc comparisons were verified using random effects models to analyse longitudinal evolution of variables.