Table 6 Cumulative effects of combined risk genotypes (rs7101916 TT and rs28372683 AA) on the susceptibility to HCV infection.

From: Genetic mutations in NF-κB pathway genes were associated with the protection from hepatitis C virus infection among Chinese Han population

Variables

Group A

Group (B + C)

Group (B + C)/Group A

n

n

OR (95% CI)a

P a

0

302

277

1

 

1

127

80

0.696 (0.492–0.984)

0.040

2

1

4

4.112 (0.407–41.595)

0.231

Trend

   

0.087b

1–2

128

84

0.725 (0.515–1.021)

0.065

  1. Abbreviations: HCV, hepatitis C virus; OR, odds ratio; 95% CI, 95% confidence interval.
  2. Group A: controls; Group B: spontaneous clearance subjects; Group C: persistent infection patients. Group (B + C): HCV-infected individuals.
  3. aLogistic regression model, adjusted for gender, age and routes of infection.
  4. bCochran–Armitage trend test.
  5. Bold type indicates statistically significant results.
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