Figure 6

Effect of DF2726A treatment on oxaliplatin-induced neurotoxic signalling pathways in neurons. Representative blots of p-FAK, p-JAK2, p-STAT3, PI3K and p-cortactin and relative quantifications in control (CTR), oxaliplatin (Oxa)-, oxaliplatin + DF2726A (Oxa + DF)- and DF2726A (DF)-treated neurons. ***P < 0.0005; **P < 0.005; *P < 0.05 vs control; +P < 0.05 vs Oxa, unpaired t-test. Data are expressed as mean ± SEM; n 3.