Figure 4 | Scientific Reports

Figure 4

From: Contactin 1 modulates pegylated arginase resistance in small cell lung cancer through induction of epithelial–mesenchymal transition

Figure 4

Knockdown of CDH17 and IGF2BP1 had very limited influence on BCT-100 resistance and EMT phenotype. (a) The cell survival was comparable in CDH17 silenced arm, scrambled and control group, and exposure time was 3 days. (b) CDH17 was downregulated while vimentin and N-cadherin were unaltered in the CDH17-silenced group. (c) The survival rate in the IGF2BP1 silenced arm, scrambled and control group. (d) IGF2BP1, vimentin and N-cadherin were tested by Western blot. *P < 0.05, **P < 0.01, ***P < 0.001.

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