Table 3 SRVS and ANOVA analysis of optimal gene expression classifiers in 14 schizophrenia-related datasets.

From: A core collection of pan-schizophrenia genes allows building cohort-specific signatures of affected brain

 

CR1

CR2

CR3

G1

G2

G3

P1

P2

P3

GSE12649

89.86

75.36

59.42

141

1

1276

<2.00e-4

<2.00e-4

0.12

GSE12654

92.86

89.29

60.71

163

10

1112

<2.00e-4

<2.00e-4

0.45

GSE12679

85.19

100

66.67

30

52

1440

<2.00e-4

<2.00e-4

0.07

GSE17612

90.20

88.24

52.94

30

60

1440

<2.00e-4

<2.00e-4

0.17

GSE21138

86.44

74.58

66.10

31

19

802

<2.00e-4

2.80e-3

0.64

GSE21935

88.10

85.71

64.29

675

27

1440

<2.00e-4

<2.00e-4

2.52e-2

GSE26927

93.85

89.23

69.23

64

40

1392

<2.00e-4

1.60e-3

0.93

GSE35974

89.36

84.04

64.89

28

14

1469

<2.00e-4

<2.00e-4

0.92

GSE35977

82.18

77.23

71.29

290

107

1469

<2.00e-4

2.00e-4

5.00e-3

GSE35978

53.38

71.28

52.31

27

17

1469

8.06e-2

<2.00e-4

0.24

GSE53987

55.34

68.93

52.43

58

2

1440

<4.80e-3

4.00e-4

1.00

GSE62191

79.66

76.27

54.24

44

11

693

<2.00e-4

<2.00e-4

0.48

GSE87610

90.51

86.13

74.45

517

238

1406

<2.00e-4

<2.00e-4

0.02

GSE93987

87.28

86.71

75.72

108

9

1429

<2.00e-4

<2.00e-4

0.65

  1. Note: CR: classification accuracy. CR1: CR by SRVS Score; CR2: CR by PValueSCore (ANOVA); CR3: CR built upon all the 1518 schizophrenia-related genes that were also included in a dataset; G1: Amount of genes selected by SRVS Score; G2: Amount of genes selected by PValueSCore (ANOVA); G3: Amount of all schizophrenia-related genes in each dataset; P1: Permutation p-value by SRVS Score classifier; P2: Permutation p-value by PValueSCore (ANOVA) classifier; P3: Permutation p-value after using all schizophrenia-related genes present in a given dataset as a classifier.
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