Figure 5
Light-stimulation of PPG neurons in the GCL induces excitatory-postsynaptic currents in granule cells. (a) (top) Schematic representation as in Fig. 2 with electrode placement on the GCs, and optical stimulation of the GCL (blue ellipse). (bottom) Photomicrograph of electrode placement on a granule cell in the GCL. (b) Raster plot representing cell-attached recordings from a granule cell and (*) a representative recording. (c) (top) rGanule cells do not receive IPSCs (Vhold = + 0 mV) after light stimulation of PPG neurons, but (bottom) receive EPSCs (Vhold = −70 mV). (d,d’) (top) Light-evoked EPSCs recorded in a single GC under control ACSF condition (Control) and (bottom) following bath application of APV and NBQX. Statistical analyses and notations as in Fig. 3f’,g’.
