Table 3 Variation in performance across scanners by means of multiple linear regression analyses (n = 42; n = 7 per scanner).

From: Performance of five automated white matter hyperintensity segmentation methods in a multicenter dataset

Method

GE Signa HDxt

1.5T

GE Signa HDxt

3T

GE Discovery

MR750 3T

Philips Ingenuity

3T

Philips Ingenia

3T

Philips Achieva

3T

Cascade

0.09 [−0.09; 0.27]

−0.06 [−0.24; 0.12]

−0.08 [−0.26; 0.10]

0.03 [−0.15; 0.21]

0.003 [−0.18; 0.18]

0.01[−0.17; 0.19]

kNN-TTP

0.01 [−0.08; 0.10]

−0.06 [−0.15; 0.03]

−0.03 [−0.12; 0.07]

0.02 [−0.08; 0.11]

0.03 [−0.06; 0.12]

0.03 [−0.06; 0.12]

Lesion-TOADS

0.12 [−0.08; 0.33]

0.04 [−0.17; 0.24]

−0.05 [−0.26; 0.16]

−0.12 [−0.33; 0.08]

0.10 [−0.11; 0.30]

−0.08 [−0.29; 0.12]

LST-LGA

0.02 [−0.11; 0.14]

−0.04 [−0.17; 0.09]

−0.03 [−0.16; 0.10]

−0.04 [−0.17; 0.09]

0.07 [−0.05; 0.20]

0.02 [−0.10; 0.15]

LST-LPA

0.06 [−0.07; 0.20]

−0.10 [−0.24; 0.03]

−0.09 [−0.23; 0.05]

−0.01 [−0.15; 0.13]

0.11 [−0.03; 0.24]

0.03 [−0.10; 0.17]

  1. Data are represented as unstandardized beta coefficients with 95% confidence intervals. We assessed whether the DSC (as an outcome) depended on scanner (as a categorical variable with each scanner being compared to all other scanners as the reference) using linear regression analysis. A significant relation between a certain scanner and the DSC (family wise error rate corrected p-value of <0.05 using a Bonferroni correction) indicates that the performance (in terms of spatial correspondence with the reference segmentation) was biased for that segmentation method by the use of that scanner (compared to the other scanners). As can be seen in the table, no significant relations were seen for any of the methods.