Figure 4 | Scientific Reports

Figure 4

From: Surgical fat removal exacerbates metabolic disorders but not atherogenesis in LDLR−/− mice fed on high-fat diet

Figure 4

Aggravated insulin resistance in the fat-removed LDLR−/− mice. (a) Glucose tolerance test (GTT) after 1 week’s recovery from the fat removal surgery. (b) Area under curve of figure (a). (c) Plasma glucose level after 10 weeks on the HFD feeding. (d) Plasma insulin level after 10 weeks on the HFD feeding. (e) Glucose tolerance test (GTT) after 10 weeks on the HFD feeding. (f) Area under curve of figure (e). (g) Insulin tolerance test (ITT) after 11 weeks on the HFD feeding. (h) Area under curve of figure (g), n = 8–9 for each group, *P < 0.05, **P < 0.01. (I,j) Western-blot analysis of p-Akt (Ser473) and total Akt in the liver (i) and skeletal muscle (j), n = 6 for each group. FR: Fat removal.

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