Figure 1
From: Claudin-1 decrease impacts epidermal barrier function in atopic dermatitis lesions dose-dependently
Cldn-1 immunointensity levels in a new Northern German cohort. (a) Cldn-1 immunostaining-intensity in stratum granulosum (SG), upper stratum spinosum (uSSP) and lower SSP/stratum basale (lSSP/SB) of healthy skin normalized to the sample with highest immunointensity in the respective layer. Dots of the same color belong to the same individual. (b) Immunointensity of Cldn-1 in SG, uSSP and lSSP/SB in healthy, non-lesional and lesional AD skin. Mean + SEM. n = 13 per group. *:significant compared to healthy control; # significant compared to non-lesional skin. a.u. arbitrary units.
