Figure 7

The image displays observations from MRI images and computational reconstruction of the same observations at observational time-points, i.e. 2 hours, 6 hours, 24 hours and 48 hours after the first MRI with administration of CSF tracer in NPH1. Row (A) shows the observations estimated from MRI images. Row (B) shows the reconstructed observations with α = 0.0001, β = 10.0, γ = 1.0 and 48 time steps. Row (C) shows reconstructed observations with α = 10−6, β = 1.0, γ = 0.01 and 48 time steps. Row (D) shows reconstructed observations with α = 10−6, β = 10.0, γ = 1.0 and 48 time steps. The color-bar was restricted to the range (0.0–0.8).