Figure 1

Evaluation of the OVX mouse model. (A) Micro-CT section, Toluidine blue staining, and Calcein double-labeling of femur bone. (B) OVX mice had lower BMD as compared to the controls. (C) BV/TV of femurs were measured by micro-CT. (D) Calcein double-labeling–based quantification of bone formation rate per bone surface (BFR/BS) in femurs.