Figure 2

Correlation of biomarker with focused preference index in males. Scatter plot showing negative correlation of focused preference index between plasma acetylcholine (A–C) and nicotinic acid (D–F) in MDD and HC males. Linear regression lines with dot plots showing relationship between focused preference index and (A) acetylcholine among all males (N = 44), (B) acetylcholine among MDD males (N = 22), (C) acetylcholine among HC males, (D) nicotinic acid among all males (N = 44), (E) nicotinic acid among MDD males (N = 22), and (F) nicotinic acid among HC males (N = 22). MDD major depressive disorder, HC healthy controls.