Figure 3
From: Dual mechanisms of ictal high frequency oscillations in human rhythmic onset seizures
Multiunit coupling to HFOs. (a) a single example pre-recruitment discharge recorded on the MEA showing broadband LFP (gray), filtered in the gamma range (cyan) and BHF range (magenta). MUA event times are shown in black. (b) an example post-recruitment discharge, showing the same signals color coded in the same way as in A. (c) A circular histogram counting multiunit event times for every 10 degrees of phase of the dominant frequency. Blue bins show coupling during pre-recruitment discharges, and red bins show coupling during post-recruitment discharges. (d) A circular histogram counting all multiunit event times in a single seizure for every 10 degrees of phase of the dominant frequency. Blue bins show coupling during pre-recruitment discharges, and red bins show coupling during post-recruitment discharges. (e) An example hippocampal unit that was recruited into the seizure. Blue bins show coupling during pre-recruitment discharges, and red bins show coupling during post-recruitment discharges. (f) An example hippocampal unit that was not recruited into the seizure. Blue bins show coupling during pre-recruitment discharges, and red bins show coupling during post-recruitment discharges.
