Figure 7
From: UBC9 coordinates inflammation affecting development of bladder cancer
Inflammation and cancer stem cell-like population increased in UBC9-low bladder cancer samples. (A) Heatmaps of UBC9-signature and proliferation-signature28. 52 case of bladder cancer samples were divided into high, medium and low groups according to the mRNA expression of UBC9. proliferation-signature, UBC9-signature CD44 and IL6 were shown. (B) The correlation between IL6 levels and CD44 levels. (C) Heatmap of mean level cancer stem cells markers. Samples were divided into two groups according to the expression of UBC9 and the expression of cancer stem cells markers were detected by CyTOF. (D) Representative tSNE plot from sample1 (UBC9-up) and sample4 (UBC9-down). The blue circle indicated the CD44-positive cell population.
