Figure 5
From: Microbiota attenuates chicken transmission-exacerbated campylobacteriosis in Il10−/− mice
Cj-P1-DCA-Anaero induced less colitis compared to Cj-P1. Cohorts of 5–9 SPF Il10−/− mice were orally gavaged daily with clindamycin for 7 days. The mice were then infected with a single dose of 109 CFU /mouse C. jejuni of Cj-P0 (5 mice), Cj-P1 (9 mice), or Cj-P1-DCA-Anaero (5 mice) and were euthanized 8 days post-infection. (A) H&E staining showing representative intestinal histology of C. jejuni-induced colitis in Il10−/− mice. (B) Quantification of histological intestinal damage score. Scale bar is 200 μm. *P < 0.05. Data represent means ± SEM. Results are representative of 3 independent experiments.
