Figure 4
From: Role of PARP1-mediated autophagy in EGFR-TKI resistance in non-small cell lung cancer
Effects of PARP1 on cell autophagy in HCC-827IR, H1975, and H1299 cells. (A) Knockdown of PARP1 by siRNA-PARP1 in HCC-827IR, H1975, and H1299 cells. Western blot measured protein expression. The data represent means ± SD of three independent experiments, *P < 0.05 versus untreated **P < 0.001 versus untreated, (Because of the films before imaging were cut, we couldn’t further provided fuller-length original blots). (B) Colony proliferation assay determined cell proliferation. PARP1 in HCC-827IR, H1975, and H1299 cells was knocked down by siRNA. Cell growth was determined by crystal violet staining. The data represent means ± SD of three independent experiments. (P < 0.05).
