Figure 5
From: Modulation of circadian clock by crude drug extracts used in Japanese Kampo medicine

Effects of 8 major ingredients of hit crude drugs. Luminescent traces (top) and dose-dependent effects on the circadian period (middle) and phase (bottom) in U2OS cells. Values are the mean of six replicates ± SD and were analyzed using one way ANOVA, followed by Dunnett’s multiple comparisons test (*p < 0.05, **p < 0.01, ***p < 0.001, **** p < 0.0001).