Figure 2

Association of the average SLC6A4 methylation value with the cumulative incidence (%) of composite cerebro-cardiovascular events, stratified by SI status immediately after stroke (within 2 weeks). Cox proportional hazards models were used for analyses of the overall cohort, and for analyses stratified by SI after adjustment for age, NIHSS score, previous history of stroke, presence of cardiac disease, and depression (according to the DSM-IV criteria) within 2 weeks after stroke. The interaction effect between average SLC6A4 methylation value and SI on composite CCVEs was not significant (p = 0.113). Abbreviations: SI, suicidal ideation; NIHSS, National Institutes of Health Stroke Scale; DSM-IV, Diagnostic and Statistical Manual of Mental Disorders, 4th edition.