Figure 2

RLE reduced viability of RA-FLS. (A) CCK-8 assays in IL-6/sIL-6R-stimulated synoviocytes. Cell viability results are from 3 independent experiments. Viability of RLE-untreated cells was regarded as 100%. *P < 0.05, **P < 0.01 vs. RLE-untreated (24 h) group. #P < 0.05, ##P < 0.01 vs. RLE-untreated (48 h) group. (B) Crystal violet staining of IL-6/sIL-6R-stimulated synoviocytes. Representative images are shown in the upper panel, and quantitative results are shown in the lower panel (n = 3). (C) CCK8 assays in IL-6/sIL-6R-stimulated L929 cells. (D) CCK8 assays in IL-6/sIL-6R-stimulated MIHA cells. In (C,D), cell viability results are from 3 independent experiments. In (B–D), *P < 0.05, **P < 0.01 vs. RLE-untreated group whose cell viability was regarded as 100%.