Table 2 Risk factors for tumor recurrence.

From: Associations of pathological diagnosis and genetic abnormalities in meningiomas with the embryological origins of the meninges

 

Univariate

Multivariate

Hazard ratio

p value

95% CI

Hazard ratio

p value

95% CI

Female

0.76

0.37

0.42–1.38

   

Age ≥ 65

1.49

0.21

0.80–2.78

   

Simpson grade 1–3

0.16

9.7 × 10–10

0.09–0.29

0.21

1.9 × 10–6

0.11–0.39

MIB-1 LI ≥ 3

3.33

1.1 × 10–4

1.81–6.14

1.81

0.14

0.82–3.98

Meningothelial

0.72

0.24

0.41–1.25

   

Transitional

0.96

0.92

0.43–2.14

   

Fibrous

0.47

0.11

0.19–1.19

1.00

0.99

0.32–3.14

WHO grade II

6.44

3.9 × 10–9

3.46–12.0

4.99

1.2 × 10–4

2.20–11.3

Neural crest

1.00

0.99

0.58–1.75

   

Paraxial mesoderm

1.07

0.81

0.61–1.90

   

Dorsal mesoderm

0.83

0.70

0.33–2.10

   

AKT1 mutation

0.60

0.39

0.19–1.94

   

KLF4 mutation

0.67

0.55

0.11–2.15

   

POLR2A mutation

2.42

0.09

0.83–5.58

4.08

1.7 × 10–2

1.28–13.0

NF2 mutation or 22q loss

1.48

0.18

0.84–2.72

1.81

0.15

0.81–4.04

  1. LI indicates labelling index, ST-med supra-tentorial-medial, ST-ant/lat supra-tentorial-antero-lateral, ST-post/lat supra-tentorial-postero-lateral, CI confidence interval.
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