Figure 4
Differences of eGFR trajectories during follow-up according to HCV infection among normal renal function individuals and those with different stages of CKD. The mean slope of eGFR decline was − 6.56 mL/min/1.73 m2/year vs. − 2.27 mL/min/1.73 m2/year (p < 0.001) in HCV infected and non-HCV infected normal renal function subjects (A); − 4.85 mL/min/1.73 m2/year vs. − 4.21 mL/min/1.73 m2/year (p = 0.698) in HCV infected and non-HCV infected mild CKD patients (B) and − 4.14 mL/min/1.73 m2/year vs. − 0.9 mL/min/1.73 m2/year (p < 0.001) in HCV infected and non-HCV infected moderate to severe CKD patients (C), respectively. The eGFR change was presented as mean and confidential interval (CI). Mild CKD denoted stage 1–2 CKD, and moderate to severe CKD, stage 3–5 CKD. CKD, chronic kidney disease; eGFR, estimated glomerular filtration rate; HCV, hepatitis C virus infection. * p < 0.05, annual eGFR of non-HCV versus HCV; # p < 0.05, eGFR slope of non-HCV versus HCV.
