Figure 4

Tri-nucleotide motif score. (A) Copy number aberration analysis of all technical replicates containing fragments with tri-nucleotide motif scores less than or greater than − 0.3, − 0.15, 0, 0.15, and 0.3. The CCF of all the random samples is shown relative to median CCF from unselected data. (B) The average relative copy number values from the 10 replicates of patient 2. The different colors indicate results from using fragments with no selection, fragments with tri-nucleotide motif score less than or equal to − 0.3, − 0.15, 0, and greater than or equal to 0, 0.15, 0.3. (C) The fragment size distribution in the control pool and HGSOC patient 5 of fragments with no selection, fragments with tri-nucleotide motif score less than or equal to -0.3 and greater than or equal to 0.3.