Table 2 Metabolites found to be significant between vehicle-injected Ptn-Tg mice and vehicle-injected Wt mice.

From: Metabolomics and biochemical alterations caused by pleiotrophin in the 6-hydroxydopamine mouse model of Parkinson’s disease

Feature

P-value

% VAR (Ptn-Tg vs Wt)

Name

Polarity

Adduct

[email protected]

0.0004

− 37.6

3-Hydroxy-2-methylpyridine-4,5-dicarboxylate

POS

M+H

[email protected]

0.0076

− 33.2

Aspartic acid

POS

M+H

[email protected]

0.0120

− 28.7

5-Oxo-d-proline/d-pyroglutamic acid/d-5-pyrrolidone-2-carboxylic acid

POS

M+H

[email protected]

0.0360

− 16.5

1,2-Diamino-4-nitrobenzene/N-dimethyl-2-aminoethylphosphonate; 2-dimethylaminoethylphosphonate

POS

M+H

[email protected]

0.0360

− 36.6

Ser Ala Cys

POS

M+H

[email protected]

0.0256

75.2

Bis (2-hydroxypropyl) amine

POS

M+H

[email protected]

0.0016

− 45.9

Methylnoradrenaline/epinephrine/normetanephrine

POS

M+H

[email protected]

0.0256

− 49.4

Dihydrozeatin

POS

M+H

[email protected]

0.0028

− 39.7

Methylmalonic acid semialdehyde/2-methyl-3-oxo-propanoic acid/3-methyl pyruvic acid/Acetoacetic acid

POS

M+H

[email protected]

0.0076

39.4

ent-9-L1-PhytoP

POS

M+H

[email protected]

0.0076

57.0

d-erythro-sphingosine C-15

POS

M+H

[email protected]

0.0120

105.9

N-Linoleoyl GABA/N-cis-octadec-9Z-enoyl-l-homoserine lactone

POS

M+H

[email protected]

0.0004

− 45.1

Retinol

POS

M+H

[email protected]

0.0176

43.4

(24Z),26-hydroxydesmosterol

POS

M+H

[email protected]

0.0496

28.8

Stoloniferone G

POS

M+H

[email protected]

0.0048

− 26.6

l-carnitine

POS

M+H

[email protected]

0.0360

− 39.5

Tetradecanoylcarnitine

POS

M+H

[email protected]

0.0028

− 51.9

O-palmitoleoylcarnitine

POS

M+H

[email protected]

0.0016

− 40.2

O-arachidonoylcarnitine

POS

M+H

[email protected]

0.0256

− 46.2

O-oleoylcarnitine/elaidic carnitine

POS

M+H

[email protected]

0.0176

− 44.6

Neuraminic acid/deoxyguanosine/adenosine

NEG

M−H

[email protected]

0.0360

− 34.8

Axillarenic acid/tetracosanedioic acid

POS

M+H

[email protected]

0.0496

− 34.8

Amino-octadecanoic acid

POS

M+H

[email protected]

0.0004

− 47.0

Norchenodeoxycholic acid

POS

M+H

[email protected]

0.0016

− 40.6

10-oxo-nonadecanoic acid

POS

M+H

[email protected]

0.0004

− 55.3

2-oxo-heneicosanoic acid

POS

M+H

[email protected]

0.0004

− 46.9

Glycidyl oleate

POS

M+H

[email protected]

0.0360

− 41.8

Amphimic acid B

POS

M+H

[email protected]

0.0120

55.4

DG(43:5)

POS

M+H

[email protected]

0.0360

− 21.9

DG(38:6)

POS

M+H

[email protected]

0.0028

− 44.6

DG(38:7)

POS

M+H

[email protected]

0.0004

− 39.2

DG(36:4)

POS

M+H

[email protected]

0.0004

− 49.0

DG(38:5)

POS

M+H

[email protected]

0.0004

− 44.5

DG(38:4)

POS

M+H

[email protected]

0.0256

− 29.9

DG(38:4)

POS

M+H

[email protected]

0.0120

14.0

PC(35:6)

POS

M+H

[email protected]

0.0360

− 27.4

PC(37:4)

POS

M+H

[email protected]

0.0028

− 12.5

PC(38:4)

POS

M+H

[email protected]

0.0360

− 31.2

PC(35:1)

POS

M+H

[email protected]

0.0496

− 15.2

PC(38:2)

POS

M+H

[email protected]

0.0076

− 37.5

PE-NMe(11D5/13M5)

NEG

M−H

[email protected]

0.0120

68.9

PG(37:0)

NEG

M−H

[email protected]

0.0004

55.5

PGP(38:0)

POS

M+H

[email protected]

0.0028

135.6

SM(36:2)

POS

M+H

[email protected]

0.0120

70.1

SM(36:1)

POS

M+H

[email protected]

0.0076

60.6

SM(37:1)/PE-Cer(40:1)

POS

M+H

[email protected]

0.0360

155.4

PI(38:6)

NEG

M−H

[email protected]

0.0256

60.3

PI(36:4)

NEG

M−H

[email protected]

0.0120

133.0

PI(38:5)

NEG

M−H

[email protected]

0.0120

45.6

PI(38:4)

NEG

M−H

[email protected]

0.0028

59.6

PI(44:12)

NEG

M−H

[email protected]

0.0496

− 26.9

GlcCer(42:1)

NEG

M−H

[email protected]

0.0256

− 48.7

GlcCer(42:0)

NEG

M−H

[email protected]

0.0028

− 61.5

Ganglioside GM3 (36:1)

NEG

M−H