Figure 1

Pathologic features of NKTCL in children and adolescents, lymph nodes (case 21). (A) Lymphoid cells were medium-large in size with coagulative necrosis (HE ×200). Neoplastic cells were positive for (B) CD3 and (C) CD56 (×200). (D) CD5 negative was expressed in this case (×200). (E) The tumor cells showed focal positivity for CD30 (×200). (F) Lymphoid cells were EBV positive by ISH detection, > 100 per high-power field in the hot spot region (×200).