Figure 4
CLIP-seq analysis revealed the RNA binding features of PCBP1 in T lymphoma cell line. (A) Bar plot showed the reads distribution across reference genome. (B) Peak reads density in 5′UTR, CDS and 3′UTR. These three regions of each gene were separated into 100 bins, the UPF1 peak reads in each bin was calculated. The reads density of UPF1 peaks in all genes were plotted. (C) Venn diagram showed the overlap peaks in two IP samples. (D) Bar plot showed the overlap peaks reads distribution across reference genome. (E) Motif analysis showed the top 5 overlapped peaks preferred bound motifs of PCBP1 by HOMER software. (F) Bar plot exhibited the most enriched GO biological process results of the overlap PCBP1-bound genes, that making use of analyses by Metascape.
