Table 1 Demographic data and histopathological information in the primary cohort.

From: Development and validation of multivariate models integrating preoperative clinicopathological and radiographic findings to predict HER2 status in gastric cancer

Characteristics

HER2 negative (n = 114)

HER2 positive (n = 23)

p

Demographic data

Gender

  

0.481

Male

81

18

 

Female

33

5

 

Age (year)

  

0.092

< 60

46

5

 

≥ 60

68

18

 

Postoperative histopathological information

Major ___location

  

0.008*

Cardia

24

12

 

Body

44

6

 

Antrum

46

5

 

T stages

  

0.491

1

6

2

 

2

20

5

 

3

59

13

 

4

29

3

 

N stages

  

0.334

N0

33

9

 

N1–3

81

14

 

Lauren classificationa

  

0.003*

Intestinal type

44

18

 

Diffuse type

32

2

 

Mixed type

37

3

 

Lymphovascular invasion

  

0.842

Absent

47

10

 

Present

67

13

 

Neural invasion

  

0.050

Absent

31

11

 

Present

83

12

 
  1. HER2 human epidermal growth factor receptor 2. aNot applicable for one patient; *p < 0.05 with chi-square test or Fisher's exact test (n < 5).
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