Figure 1

IgG and IgM specific responses against the most significant immunodominant linear epitopes within different clinical groups. Responses against the most significant peptides highlighted in bold in Table 2. (A) IgG responses toward spike peptides S139, S140, S204 and S287. (B) IgG responses toward nucleocapsid peptides N041, N056, N099 and N100. (C) IgM response toward membrane peptides M002 and M003 and nucleocapsid peptide N064. p values for the comparison of uninfected versus infected subjects are all significant for the chosen peptides of Table 2. The p values for the comparison of the asymptomatic group versus the symptomatic group were always non-significant. Here, p values are shown under the graphs only if the comparison between the severe group and the asymptomatic groups by the Student's t-test is significant.