Figure 1

Quantitative analysis scheme. Starting from the original OCT and OCTA data, we obtained the thickness measurements of the choroidal layers by considering five fixed samplings, subfoveal, at 750 µm (right–left) and at 1500 µm (right–left) (upper left part of the scheme). Choroidal vascularity index was calculated after the segmentation and the binarization of the choroid (upper central part of the scheme). Moreover, we used the automatic ETDRS-9 sector grid measurements of retinal layers (upper right part of the scheme). With respect to OCTA, we obtained the enface reconstructions of vascular plexa (lower central part of the scheme). After the binarization of the images and the exclusion of the FAZ area, we calculated vessel density metric (lower left part of the scheme). In addition, choriocapillaris porosity was calculated after the careful detection of the choriocapillaris flow voids (highlighted in red) (lower right part of the scheme).