Figure 2
From: RNU12 inhibits gastric cancer progression via sponging miR-575 and targeting BLID
RNU12 overexpression inhibited GC cells in terms of the proliferation, migration, and invasion. (A) Real-time PCR on RNU 12 expression in AGS and MGC 803 cells; (B,C) The impact of RNU 12 overexpression on the cell vitality under the measurement of MTT assay; (D,E)The impact of RNU 12 overexpression on cell colony formation; (F,G) The impact of RNU 12 overexpression on cell cycle distribution under FACS; (L–O) The impact of RNU 12 overexpression on cell migration under WHA; (P,Q) The impact of RNU 12 overexpression on cell invasiveness under transwell invasive assay (TIA); (H–K) qRT-PCR and WB detected the expressions regarding proliferation-related-genes of Bcl-2, CCND1, and PCNA; (R,S) The expression exhibited by invasion/metastasis-related-genes, E-cadherin, VIMENTIN and N-cadherin according to WB. *P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.0001.
