Figure 7
The knockdown of Nrf2 inactivated the inhibitory effect of 4-OI on CRC cell death. (A, B) Compared with oxaliplatin or lobaplatin alone, 4-OI combined with oxaliplatin or lobaplatin had no difference in the viability of the Nrf2 knockdown of CRC cells. (C–E) In the colony formation assay, compared with oxaliplatin or lobaplatin alone, 4-OI combined with oxaliplatin or lobaplatin had no difference in the colony formation of the Nrf2 knockdown of CRC cells. (F–I) 4-OI combined with oxaliplatin or lobaplatin had no difference in apoptosis of the Nrf2 knockdown of CRC cells compared with oxaliplatin or lobaplatin alone. Data are shown as the mean ± SD, ns (not significant).
