Figure 1 | Scientific Reports

Figure 1

From: Identification of endoplasmic reticulum stress-related signature characterizes the tumor microenvironment and predicts prognosis in lung adenocarcinoma

Figure 1

Flowchart of the prognostic model development and subsequent analyses in LUAD. The process initiates with the identification of prognostically significant genes from the pool of ER-stress-related-genes (ERSRGs) using COX regression. This foundational step facilitates the creation of a robust prognostic model via consensus clustering, segregating into two distinct molecular subgroups. With the model established, a series of in-depth analyses ensue, including differential gene expression, immune infiltration, functional enrichment, and clinical correlations, culminating in the formulation of an optimized nomogram for LUAD prognosis.

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