Table 3 Adjusted odds ratios for respiratory outcomes before NICU discharge among very low birth weight infants received different courses and duration of mechanical ventilation.

From: Effect of different courses and durations of invasive mechanical ventilation on respiratory outcomes in very low birth weight infants

Outcome

Number of mechanical ventilation coursesa

Duration of mechanical ventilation b

1 course

2 courses

 ≥ 3 courses

 ≤ 7d

8-21d

22-35d

 ≥ 36d

BPD

Reference

1.11 (0.88, 1.39)

1.07 (0.72, 1.60)

Reference

1.98 (1.59, 2.45)

4.37 (3.17, 6.03)

18.44 (10.98, 30.99)

Severe BPD

Reference

2.17 (1.07, 4.40)

2.59 (1.02, 6.61)

Reference

8.42 (3.22, 22.01)

27.82 (9.08, 85.22)

616.45 (195.79, > 999.999)

Death

Reference

1.80 (1.17, 2.77)

2.52 (1.41, 4.51)

Reference

1.70 (1.01, 2.84)

6.31 (3.53, 11.26)

3.78 (1.79, 8.00)

Requirement of home oxygen therapy

Reference

1.20 (0.94, 1.54)

1.62 (1.07, 2.43)

Reference

1.82 (1.42, 2.34)

3.75 (2.65, 5.30)

4.24 (2.74, 6.57)

Discharged with requirement of non-invasive/invasive mechanical ventilation

Reference

1.47 (0.96, 2.25)

1.89 (1.04, 3.42)

Reference

1.70 (1.03, 2.80)

5.59 (3.14, 9.95)

3.00 (1.45, 6.23)

  1. aAdjusted for gestational age, birth weight, sex, small for gestational age, 5-min Apgar score, treatment with surfactant, DART treatment, PDA, NEC, sepsis, and mechanical ventilation duration (analyzed as grouping variable).
  2. bAdjusted for gestational age, birth weight, sex, small for gestational age, 5-min Apgar score, treatment with surfactant, DART treatment, PDA, NEC, sepsis, and mechanical ventilation courses (analyzed as grouping variable).
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