Figure 4 | Scientific Reports

Figure 4

From: NKG2D knockdown improves hypoxic-ischemic brain damage by inhibiting neuroinflammation in neonatal mice

Figure 4

NKG2D knockdown alleviated neuroinflammation in neonatal HIBD mice. (A, B) Representative images and analysis of Iba-1-positive microglia in the cortex and hippocampal CA1 subregions. (C, D) Representative images and analysis of GFAP-positive astrocytes in the cortex and hippocampal CA1 subregions. (E) Expression levels of TNF-α and IL-6 were measured by ELISA. The data are expressed as the mean ± SEM (n = 6/group). **p < 0.01 and ##p < 0.01 (two-tailed Student’s t-test for comparisons between two groups).

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