Table 5 Factors associated with iPFS and mOS (cox analysis).

From: Treatment outcomes and prognostic factors in patients with driver mutant non-small cell lung cancer and de novo brain metastases

 

HR

95% CI

p

mOS associated variables

 Age

   < 65

  

0.001

   > 65

1.8

1.3–2.5

 ECOG PS

  0–1

  

0.02

   > 2

1.54

1.01–2.21

 Extracranial metastasis

  No

  

0.048

  Yes

1.7

1.0–2.87

iPFS associated variables

 Age

   < 65

  

0.005

   ≥ 65

1.5

1.1–2.1

 ECOG PS

  0–1

  

0.32

   ≥ 2

1.18

0.85–1.63

 Extracranial metastasis

  No

  

 < 0.001

  Yes

2.4

1.5–3.9

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