Figure 5 | Scientific Reports

Figure 5

From: Discovering therapeutic possibilities for polycystic ovary syndrome by targeting XIST and its associated ceRNA network through the analysis of transcriptome data

Figure 5

Construction of the ceRNA network for XIST-miRNAs-mRNAs. (A) The overlapping DE miRs and XIST-targeted miRNAs. (B) Pearson correlation analysis of the 12 miRNAs with XIST and 25 XIST-related genes. Light colors represent a positive correlation, while dark colors represent a negative correlation. The genes with no significant correlation were shown with zero correlation. (C) Sankey diagram indicating interactions between XIST and their matched miRNAs and mRNAs. Each rectangle represents a gene, and the connection degree of each gene is visualized based on the size of the rectangle. ceRNA, Competitive endogenous RNA; DEmiRs, differential expression of microRNAs; miRNAs, microRNAs.

Back to article page