Table 1 Clinicopathological characteristics.
|  | Train (N = 12,040) | Test (N = 5160) | All (N = 17,200) | t/χ2 (p) |
|---|---|---|---|---|
Age | 63.41 ± 15.20 | 36.11 ± 15.54 |  | 1.161 (0.242) |
Marriage | ||||
 Married | 8199 (68.10) | 3542 (68.64) | 11,741 (68.26) | 0.496 (0.481) |
 Unmarried | 3841 (31.90) | 1618 (31.36) | 5459 (31.74) | |
Sex | ||||
 Male | 6482 (53.84) | 2795 (54.17) | 9277 (53.94) | 0.158 (0.691) |
 Female | 5558 (46.16) | 2365 (45.83) | 7923 (46.06) | |
Race | ||||
 White | 11,933 (99.11) | 5101 (98.86) | 17,034 (99.03) | 2.452 (0.117) |
 Other | 107 (0.89) | 59 (1.14) | 166 (0.97) | |
Laterality | ||||
 Left | 6417 (53.30) | 2743 (53.16) | 9160 (53.26) | 0.028 (0.868) |
 Right | 5623 (46.70) | 2417 (46.84) | 8040 (46.74) | |
Stage | ||||
 I | 9020 (74.92) | 3900 (75.58) | 12,920 (75.12) | 3.969 (0.137) |
 II | 2067 (17.17) | 897 (17.38) | 2964 (17.23) | |
 III/IV | 953 (7.92) | 363 (7.03) | 1316 (7.65) | |
Tstage | ||||
 T1 | 7565 (62.83) | 3240 (62.79) | 10,805 (62.82) | 1.831 (0.4) |
 T2 | 3563 (29.59) | 1557 (30.17) | 5120 (29.77) | |
 T3/T4 | 912 (7.57) | 363 (7.03) | 1275 (7.41) | |
Nstage | ||||
 N0 | 11,138 (92.51) | 4808 (93.18) | 15,946 (92.71) | 2.624 (0.269) |
 N1 | 584 (4.85) | 233 (4.52) | 817 (4.75) | |
 N2/N3 | 318 (2.64) | 119 (2.31) | 437 (2.54) | |
Mstage | ||||
 M0 | 11,947 (99.23) | 5134 (99.50) | 17,081 (99.31) | 3.791 (0.052) |
 M1 | 93 (0.77) | 26 (0.50) | 119 (0.69) | |
Surgery | ||||
 Surgery1 | 7625 (63.33) | 3246 (62.91) | 10,871 (63.20) | 0.279 (0.598) |
 Surgery2 | 4415 (36.67) | 1914 (37.09) | 6329 (36.80) | |
Distant LN | ||||
 None | 6471 (53.75) | 2825 (54.75) | 9296 (54.05) | 2.108 (0.550) |
 1 ~ 3 | 358 (2.97) | 161 (3.12) | 519 (3.02) | |
 > 4 | 467 (3.88) | 199 (3.86) | 666 (3.87) | |
 Others | 4744 (39.40) | 1975 (38.28) | 6719 (39.06) | |
Surg Oth Reg | ||||
 None | 11,923 (99.03) | 5125 (99.32) | 17,048 (99.12) | 3.551 (0.059) |
 Yes | 117 (0.97) | 35 (0.68) | 152 (0.88) | |
Radiation | ||||
 No | 11,922 (99.02) | 5113 (99.09) | 17,035 (99.04) | 0.182 (0.670) |
 Yes | 118 (0.98) | 47 (0.91) | 165 (0.96) | |
Chemotherapy | ||||
 No | 11,935 (99.13) | 5116 (99.15) | 17,051 (99.13) | 0.016 (0.900) |
 Yes | 105 (0.87) | 44 (0.85) | 149 (0.87) | |
 Breslow | 1.401 ± 1.793 | 1.367 ± 1.762 |  | 1.149 (0.250) |
LDH | ||||
 Unhigh | 11,656 (96.81) | 5004 (96.98) | 16,660 (96.86) | 0.328 (0.567) |
 High | 384 (3.19) | 156 (3.02) | 540 (3.14) |  |
 Mitotic | 1.94 ± 2.964 | 1.93 ± 2.99 |  | 0.390 (0.697) |
Ulceration | ||||
 No | 10,205 (84.76) | 4320 (83.72) | 14,525 (84.45) | 2.964 (0.085) |
 Yes | 1835 (15.24) | 840 (16.28) | 2675 (15.55) | |
Lnpositive | ||||
 No | 4795 (39.83) | 2011 (38.97) | 6806 (39.57) | 1.098 (0.295) |
 Yes | 7245 (60.17) | 3149 (61.03) | 10,394 (60.43) | |
DX_bone | ||||
 No | 12,020 (99.83) | 5155 (99.90) | 17,175 (99.85) | 1.192 (0.275) |
 Yes | 20 (0.17) | 5 (0.10) | 25 (0.15) | |
DX_brain | ||||
 No | 12,019 (99.83) | 5154 (99.88) | 17,173 (99.84) | 0.779 (0.377) |
 Yes | 21 (0.17) | 6 (0.12) | 27 (0.16) | |
DX_liver | ||||
 No | 12,024 (99.87) | 5156 (99.92) | 17,180 (99.88) | 0.953 (0.329) |
 Yes | 16 (0.13) | 4 (0.08) | 20 (0.12) | |
DX_lung | ||||
 No | 11,992 (99.60) | 5150 (99.81) | 17,142 (99.66) | 4.511 (0.034) |
 Yes | 48 (0.40) | 10 (0.19) | 58 (0.34) | |
Tumor size | ||||
 < 2 | 4827 (40.09) | 2052 (39.77) | 6879 (39.99) | 0.456 (0.796) |
 2–10 | 745 (6.19) | 310 (6.01) | 1055 (6.13) | |
 Other | 6468 (53.72) | 2798 (54.22) | 9266 (53.87) | |
Tumor number | ||||
 Single | 7390 (61.38) | 3226 (62.52) | 10,616 (61.72) | 1.989 (0.158) |
 Multiple | 4650 (38.62) | 1934 (37.48) | 6584 (38.28) | |
First malignant primary | ||||
 No | 2852 (23.69) | 1176 (22.79) | 4028 (23.42) | 1.621 (0.203) |
 Yes | 9188 (76.31) | 3984 (77.21) | 13,172 (76.58) | |
