Table 1 Clinical characteristics.

From: Reduction in limb-movement complexity at term-equivalent age is associated with motor developmental delay in very-preterm or very-low-birth-weight infants

 

Normal (n = 79)

Motor developmental delay (n = 11)

p-value

Infantile characteristics

Sex (female)

26 (32.9)

8 (72.7)

0.018*

Gestational age (weeks:days)

29:0 (2:6)

27:3 (2:3)

0.077

Postnatal age (weeks:days) at video recordings

11:0 (3:0)

12:3 (2:3)

0.151

Birth weight (g)

1149.2 (361.3)

1029.3 (383.0)

0.308

Global score of HINE

66.2 (7.7)

57.5 (10.1)

0.001*

Categories of GMA

  

 < 0.001*

  Poor repertoire

17 (21.5)

5 (45.5)

 

  Cramped synchronized

0 (0.0)

2 (18.2)

 

  Chaotic

1 (1.3)

2 (18.2)

 

Neonatal morbidities

1-Min Apgar score†

4.7 (2.0)

3.0 (1.9)

0.008*

5-Min Apgar score†

7.2 (1.8)

5.1 (1.8)

0.002*

Bronchopulmonary dysplasia (moderate to severe)

22 (27.8)

6 (54.5)

0.073

Antenatal steroid†

53 (67.9)

4 (36.4)

0.051

Periventricular leukomalacia

5 (6.3)

5 (45.5)

 < 0.001*

Intraventricular hemorrhage (grade III–IV)

3 (3.8)

4 (36.4)

0.004*

Invasive ventilator use (days)

10.1 (15.9)

38.2 (31.2)

0.014*

Patent ductus arteriosus

42 (53.2)

10 (90.9)

0.022*

Treatments of patent ductus arteriosus

  

0.585

  Pharmacological closure

11 (13.9)

3 (27.3)

 

  Surgical closure

11 (13.9)

1 (9.1)

 

 Retinopathy of prematurity (stage 3–5)

5 (6.3)

3 (27.3)

0.055

 Sepsis

10 (12.7)

5 (45.5)

0.006*

 Seizure

1 (1.3)

4 (36.4)

0.001*

Maternal characteristics

Maternal preeclampsia

12 (15.2)

0 (0.0)

0.348

Gestational diabetes mellitus

10 (12.7)

0 (0.0)

0.604

Multiple gestations

46 (58.2)

7 (63.6)

1.000

Maternal chorioamnionitis

23 (29.1)

2 (18.2)

0.721

  1. Values are presented as mean (standard deviation) or number of participants (percentage).
  2. HINE Hammersmith Infant Neurological Examination, GMA General Movement Assessment.
  3. *Statistically significant at p < 0.05.