Table 1 Comparison of baseline characteristics between patients receiving NART and PORT in the setting of NAC in the whole cohort and matched cohort.

From: Neoadjuvant radiochemotherapy is safe and feasible for breast conserving surgery or immediate reconstruction

 

Whole Cohort

Matched Cohort

NART

PORT

P

NART

PORT

P

Age stage

  

0.885

  

0.603

 ≤ 50

190 (49.2%)

6902 (48.8%)

 

184 (49.3%)

726 (50.8%)

 

 > 50

196 (50.8%)

7227 (51.2%)

 

189 (50.7%)

702 (49.2%)

 

Race

  

0.159

  

0.291

 White

275 (71.2%)

10,147 (71.8%)

 

266 (71.3%)

1058 (74.1%)

 

 Black

77 (19.9%)

2410 (17.1%)

 

75 (20.1%)

238 (16.7%)

 

 Others*

34 (8.8%)

1572 (11.1%)

 

32 (8.6%)

132 (9.2%)

 

Histologic grade

  

0.875

  

0.602

 I

13 (3.4%)

548 (3.9%)

 

13 (3.5%)

62 (4.3%)

 

 II

127 (32.9%)

4606 (32.6%)

 

122 (32.7%)

437 (30.6%)

 

 III

246 (63.7%)

8975 (63.5%)

 

238 (63.8%)

929 (65.1%)

 

AJCC stage

  

 < 0.001

  

0.796

 I

32 (8.3%)

1068 (7.6%)

 

32 (8.6%)

91 (6.4%)

 

 IIA

73 (18.9%)

3468 (24.5%)

 

72 (19.3%)

277 (19.4%)

 

 IIB

93 (24.1%)

3900 (27.6%)

 

92 (24.7%)

371 (26.0%)

 

 IIIA

79 (20.5%)

2925 (20.7%)

 

78 (20.9%)

307(21.5%)

 

 IIIB

69 (17.9%)

1583 (11.2%)

 

63 (16.9%)

241 (16.9%)

 

 IIIC

40 (10.4%)

1185 (8.4%)

 

36 (9.7%)

141 (9.9%)

 

T

  

 < 0.001

  

0.224

 T1

59 (15.3%)

2471 (17.5%)

 

59 (15.8%)

193 (13.5%)

 

 T2

163 (42.2%)

6921 (49.0%)

 

161 (43.2%)

614 (43.0%)

 

 T3

73 (18.9%)

2829 (20.0%)

 

72 (19.3%)

330 (23.1%)

 

 T4a–c

57 (14.8%)

1098 (7.8%)

 

50 (13.4%)

152 (10.6%)

 

 T4d

34 (8.8%)

810 (5.7%)

 

31 (8.3%)

139 (9.7%)

 

N

  

0.350

  

0.592

 N0

125 (32.4%)

4351 (30.8%)

 

121 (32.4%)

423 (29.6%)

 

 N1

165 (42.7%)

6587 (46.6%)

 

160 (42.9%)

665 (46.6%)

 

 N2

56 (14.5%)

2006 (14.2%)

 

56 (15.0%)

199 (13.9%)

 

 N3

40 (10.4%)

1185 (8.4%)

 

36 (9.7%)

141 (9.9%)

 

Breast surgery

  

 < 0.001

  

0.896

 BCS

123 (31.9%)

6105 (43.2%)

 

123 (33.0%)

476 (33.3%)

 

 Mastectomy

263 (68.1%)

8024 (56.8%)

 

250 (67.0%)

952 (66.7%)

 

Axillary surgery

  

0.005

  

0.882

 No LN removed

36 (9.3%)

776 (5.5%)

 

25 (6.7%)

89 (6.2%)

 

 Biopsy

191 (49.5%)

7075 (50.1%)

 

190 (50.9%)

716 (50.1%)

 

 Dissection

159 (41.2%)

6278 (44.4%)

 

158 (42.4%)

623 (43.6%)

 

ER

  

0.023

  

0.282

 Negative

181 (46.9%)

5808 (41.1%)

 

173 (46.4%)

618 (43.3%)

 

 Positive

205 (53.1%)

8321 (58.9%)

 

200 (53.6%)

810 (56.7%)

 

PR

  

0.016

  

0.169

 Negative

229 (59.3%)

7506 (53.1%)

 

217 (58.2%)

774 (54.2%)

 

 Positive

157 (40.7%)

6623 (46.9%)

 

156 (41.8%)

654 (45.8%)

 

HER2 (since 2010)

  

0.316

  

0.707

 Negative

171 (69.2%)

6949 (66.2%)

 

170 (69.1%)

665 (67.9%)

 

 Positive

76 (30.8%)

3551 (33.8%)

 

76 (30.9%)

315 (32.1%)

 
  1. *American Indian/AK native, Ascian/Pacific Islander.