Figure 1

Differential analysis and machine learning of gene datasets. (A) Principal component analysis (PCA) plots after correction. (Red: the GSE141024 dataset; Green: the GSE 189,993 dataset). (B) Volcano plot of differentially expressed genes between the control group and the disease group. (Red: upregulated genes; Green: downregulated genes. (C,D) Lasso regression identified 9 genes as characteristic genes for MMD. (E), SVM algorithm identifies 10 genes as characteristic genes for MMD. (F) Lasso regression and SVM algorithm-screened feature genes take intersection. (Blue: the characteristic genes identified by the SVM algorithm; Red: the characteristic genes identified by Lasso regression). SVM support vector machine, MMD moyamoya disease.