Figure 5
From: Comparison of juvenile and adult myasthenia gravis in a French cohort with focus on thymic histology
Correlation between the degree of lymphofollicular hyperplasia and anti-AChR titers. AChR+ MG patients without immunosuppressive treatments were analyzed. Data from pre- and post-JMG (A) and from YAMG and AMG (B) were pooled to reach a sufficient number of patients in each category. The degree of follicular hyperplasia was graded as follows: no GC = 0; few GCs = 1; many GCs = 2; numerous GCs = 3. For each grade the mean values ± SEM for the AChR antibodies (nmol/L) was determined. 3 outliers with titers > 2000 nmol/L were excluded to better estimate the correlation. p-values were assessed using a Kruskal–Wallis test with Dunn’s multiple comparisons tests (A) and indicated if p < 0.05.
