Table 2 Characteristics of patients included in the database.

From: Comparison of juvenile and adult myasthenia gravis in a French cohort with focus on thymic histology

MG cohort (n = 938)

Juvenile MG

Adult MG

Before puberty

After puberty

Young

Older

n = 85

n = 132

n = 457

n = 264

Age range onset

[1–13[

[13–18[

[18–30[

[30–40[

Age at MG onset in years (mean ± SEM)

10.0 ± 2.8

15.3 ± 1.3

23.5 ± 3.3

33.9 ± 2.8

% of patients

9.1

14.1

48.7

28.1

Females; n (%)

64 (75.3%)

103 (78.0%)

367 (80.3%)

205 (77.7%)

MG patients (% for known patients)

AChR positivea

70 (82.4%)

112 (84.8%)

379 (82.9%)

184 (69.7%)

AChR negative

15 (17.6%)

20 (15.2%)

78 (17.1%)

80 (30.3%)

Age at thymectomy in years (mean ± SEM)

15.5 ± 7.7

18.2 ± 5.3

26.5 ± 5.1

36.2 ± 4.0

(n; age range (yo))

(n = 77; 3–56)

(n = 125; 13–49)

(n = 439; 18–51)

(n = 240; 30–53)

Delay between MG onset and thymectomy in months (mean ± SEM)b

64.4 ± 10.6 (n = 77)

35.9 ± 5.5 (n = 125)

35.7 ± 2.3 (n = 439)

28.3 ± 2.3 (n = 240)

  1. aAChR antibodies analyzed with a Fisher’s exact test: AMG vs prepuberty JMG (p = 0.0249), postpuberty JMG (p = 0.0009) and YAMG (p < 0.0001).
  2. bDelay between MG onset and thymectomy analyzed with a one-way ANOVA test with Tukey’s multiple comparisons (as detailed in Fig. 3): pre-JMG vs post-JMG (p = 0.0012), YAMG (< 0.0001) and AMG (p < 0.0001).
  3. Values are shown in bold when they highly differed from those of the other three groups.
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