Table 1 The net drifts, local drifts, and statistical parameters for overall, and by sex, region using age-period-cohort models during 2008–2022 in Guangzhou, China.

From: Trends and age-period-cohort effect on incidence of hepatitis B from 2008 to 2022 in Guangzhou, China

Variable

Chronic HB

Acute HB

Overall

Gender stratification

Regional stratification

Overall

Gender stratification

Regional stratification

Male

Female

Central areas

Non-central areas

Male

Female

Central areas

Non-central areas

Net drifts

(95% CI)

− 3.76(− 5.96,− 1.51)*

− 4.93(− 7.14,− 2.67)*

− 1.64(− 3.87,0.65)

− 5.48(− 8.01,− 2.87)*

− 5.24(− 7.69,− 2.72)*

− 12.02(− 14.15,− 9.84)*

− 13.31(− 15.31,− 11.26)*

− 9.27(− 11.84,− 6.63)*

− 12.64(− 15.74,− 9.42)*

− 14.38(− 16.52,− 12.19)*

Local drifts (95% CI) of age group

 0–4

− 14.52(− 36.95,15.90)

− 15.59(− 38.64,16.12)

− 12.93(− 34.55,15.82)

− 15.44(− 42.81,25.01)

− 17.04(− 39.89,14.50)

− 19.05(− 28.07,− 8.91)*

− 19.26(− 27.70,− 9.84)*

− 19.01(− 29.42,− 7.05)*

− 21.24(− 34.14,− 5.82)*

− 21.07(− 29.85,− 11.19)*

 5–9

− 7.67(− 28.97,20.02)

− 10.23(− 31.80,18.17)

− 3.71(− 24.98,23.61)

− 10.38(− 35.85,25.20)

− 9.24(− 31.34,19.99)

− 4.29(− 18.63,12.58)

− 6.88(− 21.25,10.12)

− 0.74(− 15.65,16.81)

− 15.17(− 35.71,11.94)

− 2.72(− 17.47,14.67)

 10–14

− 10.44(− 29.04,13.03)

− 11.76(− 30.20,11.56)

− 8.14(− 27.32,16.11)

− 13.62(− 35.53,15.74)

− 11.16(− 30.81,14.07)

− 8.06(− 21.54,7.74)

− 10.29(− 23.50,5.19)

− 4.42(− 19.27,13.17)

− 12.54(− 33.72,15.41)

− 8.28(− 21.77,7.53)

 15–19

− 9.86(− 19.82,1.33)

− 11.23(− 21.38,0.24)

− 7.62(− 17.39,3.30)

− 11.46(− 23.51,2.48)

− 11.32(− 21.79,0.55)

− 20.49(− 29.07,− 10.87)*

− 21.90(− 30.20,− 12.61)*

− 18.05(− 27.52,− 7.34)*

− 18.07(− 29.48,− 4.82)*

− 23.34(− 32.10,− 13.45)*

 20–24

− 10.42(− 14.64,− 6.00)*

− 12.6(− 17.05,− 7.91)*

− 7.31(− 11.23,− 3.22)*

− 10.6(− 15.43,− 5.48)*

− 12.57(− 17.11,− 7.77)*

− 21.43(− 25.20,− 17.48)*

− 22.57(− 26.25,− 18.71)*

− 19.74(− 23.81,− 15.45)*

− 20.25(− 26.21,− 13.82)*

− 23.90(− 27.51,− 20.12)*

 25–29

− 11.46(− 14.34,− 8.49)*

− 13.12(− 16.08,− 10.05)*

− 8.86(− 11.64,− 5.98)*

− 13.16(− 16.37,− 9.83)*

− 12.96(− 16.11,− 9.69)*

− 21.60(− 24.34,− 18.76)*

− 22.73(− 25.27,− 20.09)*

− 19.23(− 22.49,− 15.83)*

− 20.71(− 24.77,− 16.44)*

− 24.10(− 26.77,− 21.33)*

 30–34

− 8.06(− 10.91,− 5.12)*

− 9.27(− 12.08,− 6.37)*

− 5.56(− 8.59,− 2.44)*

− 11.03(− 14.18,− 7.77)*

− 9.09(− 12.24,− 5.82)*

− 18.26(− 21.2,− 15.21)*

− 19.89(− 22.49,− 17.19)*

− 13.63(− 17.65,− 9.42)*

− 18.37(− 22.82,− 13.65)*

− 20.66(− 23.49,− 17.71)*

 35–39

− 5.56(− 8.67,− 2.34)*

− 7.13(− 10.1,− 4.07)*

− 2.18(− 5.73,1.50)

− 7.48(− 10.96,− 3.86)*

− 7.65(− 11.05,− 4.12)*

− 16.56(− 19.94,− 13.05)*

− 17.83(− 20.77,− 14.77)*

− 13.01(− 17.79,− 7.95)*

− 16.32(− 21.56,− 10.72)*

− 19.79(− 23.00,− 16.45)*

 40–44

− 2.38(− 5.94,1.30)

− 3.78(− 7.13,− 0.31)*

0.87(− 3.31,5.22)

− 2.84(− 6.76,1.25)

− 5.56(− 9.46,− 1.49)*

− 13.92(− 17.88,− 9.76)*

− 15.05(− 18.43,− 11.54)*

− 10.14(− 16.2,− 3.64)*

− 14.05(− 20.34,− 7.26)*

− 17.80(− 21.51,− 13.91)*

 45–49

− 0.50(− 4.36,3.51)

− 1.67(− 5.35,2.15)

1.99(− 2.39,6.57)

− 2.07(− 6.09,2.13)

− 2.78(− 7.22,1.87)

− 10.85(− 15.43,− 6.03)*

− 11.70(− 15.69,− 7.52)*

− 8.12(− 14.66,− 1.07)*

− 12.61(− 19.62,− 4.99)*

− 14.04(− 18.42,− 9.42)*

 50–54

3.11(− 1.23,7.65)

1.98(− 2.27,6.41)

4.83(0.22,9.65)*

− 0.35(− 4.54,4.03)

3.20(− 2.20,8.89)

− 4.51(− 10.22,1.56)

− 5.63(− 10.72,− 0.26)*

− 2.92(− 10.37,5.14)

− 8.09(− 16.09,0.68)

− 5.58(− 11.31,0.53)

 55–59

6.04(1.24,11.06)*

5.67(0.87,10.69)*

6.58(1.71,11.67)*

3.83(− 0.67,8.53)

5.87(− 0.18,12.29)

− 0.32(− 6.94,6.78)

− 1.11(− 7.24,5.44)

1.62(− 6.32,10.23)

− 1.09(− 9.80,8.46)

− 1.68(− 8.55,5.70)

 60–64

3.03(− 2.33,8.68)

2.89(− 2.53,8.61)

3.50(− 1.83,9.12)

3.03(− 2.02,8.35)

0.69(− 5.95,7.79)

− 5.23(− 12.55,2.71)

− 7.00(− 13.81,0.35)

− 1.72(− 10.64,8.08)

− 3.71(− 13.12,6.73)

− 8.39(− 15.94,− 0.16)*

 65–69

1.16(− 5.04,7.76)

0.89(− 5.43,7.63)

1.81(− 4.27,8.29)

1.26(− 4.54,7.43)

− 1.50(− 9.22,6.87)

− 5.55(− 15.10,5.08)

− 6.34(− 15.43,3.72)

− 3.83(− 14.78,8.54)

− 1.59(− 14.53,13.31)

− 10.39(− 19.94,0.30)

 70–74

− 1.02(− 8.24,6.76)

− 1.65(− 9.03,6.33)

− 0.04(− 7.08,7.53)

− 3.20(− 9.63,3.69)

− 0.94(− 10.58,9.74)

− 6.72(− 17.43,5.38)

− 8.18(− 18.26,3.14)

− 4.65(− 17.01,9.55)

− 8.64(− 22.17,7.25)

− 7.83(− 19.19,5.13)

 75–79

− 2.92(− 11.85,6.92)

− 3.21(− 12.69,7.31)

− 2.49(− 10.70,6.47)

− 6.21(− 13.97,2.25)

− 1.50(− 13.72,12.45)

− 7.25(− 19.82,7.28)

− 9.97(− 22.36,4.41)

− 3.54(− 16.89,11.95)

− 14.09(− 28.65,3.44)

− 4.01(− 18.70,13.33)

 80–84

− 1.76(− 15.67,14.44)

− 2.37(− 17.40,15.39)

− 1.14(− 13.57,13.07)

− 3.55(− 15.40,9.95)

− 1.33(− 20.71,22.78)

− 5.47(− 22.86,15.83)

− 4.45(− 21.85,16.82)

− 7.61(− 25.50,14.59)

− 2.78(− 22.68,22.25)

− 8.88(− 28.22,15.66)

  1. HB Hepatitis B; 95% CI 95% confidence interval; Net drifts represent the annual percentage change in the incidence rate based on period and birth cohort. Local drifts indicate the annual percentage change over time specific to the age group.* indicates the statistically significant (P < 0.05).
  2. Significant values are in bold.