Figure 2
Phylogenetic analysis and proposed gene loss events for LsMVP orthologues in Ecdysozoa. (a) Maximum-likelihood phylogenetic tree of selected MVP orthologues, major monophyletic clades are annotated with colored bars, taxa in bold have experimental evidence in this study. Node support in % is given for all nodes with bootstrap support < 100%, scale-bar represents substitutions per site. Taxa marked with an asterisk indicate likely presence of contaminants. The tree was rooted using the Deuterostomia as outgroup. The MSA of orthologous MVP sequences used to construct the phylogenetic tree are given in Supplementary File S2. (b) Likely parsimonious gene loss events (red circles) of Mvp projected on a consensus topology of Ecdysozoa following Howard et al.51. Taxa in bold contain MVP-orthologues and are colored in the same way as in (a). In parenthesis: number of genome records with significant (e-value < 1E−6) Blast hit/total number of records scanned. Gene loss marked with *: Possible mosaic distribution and presence of orthologues in a few taxa; + : Following Lozano-Fernandez et al.52 we assume monophyly of Acari (Acariformes + Parasitiformes) and thereby assign a single ancestral gene loss to this group. Colored nodes reference the same major diversification events in both trees (a) and (b). Pictograms were downloaded from https://phylopic.org.
