Table 2 The results of a simple regression analysis to identify the clinical factors at 3 months influencing the %ΔTKB level (n = 46).

	Standard regression coefficients	Standard error	95% CI	P
Age (years)	0.307	2.660	− 5.054 to 5.667	0.909
BMI (kg/m²)	5.677	7.949	− 10.343 to 21.697	0.479
SBP (mmHg)	− 3.885	2.493	− 8.910 to 1.139	0.126
DBP (mmHg)	− 2.082	2.591	− 7.304 to 3.140	0.426
Heart rate (beats per minute)	0.053	2.521	− 5.027 to 5.133	0.983
LVEF (%)	− 7.132	2.530	− 12.237 to − 2.026	0.007
FBS (mg/dL)	2.896	1.616	− 0.360 to 6.153	0.080
Fasting blood insulin (µU/mL)	4.337	9.661	− 15.133 to 23.807	0.656
HbA1c (%)	78.271	52.921	− 28.384 to 184.926	0.146
TG (mg/dL)	0.380	0.617	− 0.863 to 1.623	0.541
HDL (mg/dL)	1.333	2.169	− 3.038 to 5.705	0.542
LDL (mg/dL)	0.062	1.097	− 2.149 to 2.274	0.955
AST (U/L)	0.433	5.161	− 9.996 to 10.863	0.933
ALT (U/L)	− 1.732	3.210	− 8.219 to 4.755	0.592
LDH (U/L)	− 2.220	1.106	− 4.454 to 0.015	0.051
ALP (U/L)	− 0.955	1.442	− 3.868 to 1.959	0.512
γ-GTP (U/L)	0.524	1.056	− 1.610 to 2.658	0.623
TB (mg/dL)	51.981	131.100	− 212.234 to 316.197	0.694
Albumin (g/dL)	34.844	91.171	− 148.899 to 218.587	0.704
eGFR (mL/min/1.73 m²)	− 0.112	1.645	− 3.428 to 3.204	0.946
UA (mg/dL)	13.418	22.641	− 32.212 to 59.048	0.556
BNP (pg/mL)	0.143	0.384	− 0.630 to 0.917	0.711
NEFA (μEq/L)	0.463	0.092	0.277 to 0.649	< 0.001

TKB, total ketone body; CI, confidence interval; BMI, body mass index; SBP, systolic blood pressure; DBP, diastolic blood pressure; LVEF, left ventricular ejection fraction; FBS, fasting blood sugar; Hb, hemoglobin; TG, triglyceride; HDL, high-density lipoprotein cholesterol; LDL, low-density lipoprotein cholesterol; AST, aspartate aminotransferase; ALT, alanine aminotransferase; LDH, lactate dehydrogenase; ALP, alkaline phosphatase; γ-GTP, γ-glutamyltranspeptidase; TB, total bilirubin; eGFR, estimated glomerular filtration rate; UA, uric acid; BNP, B-type natriuretic peptide; NEFA, non-esterified fatty acid.

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