Figure 5 | Scientific Reports

Figure 5

From: Icariin alleviates cisplatin-induced premature ovarian failure by inhibiting ferroptosis through activation of the Nrf2/ARE pathway

Figure 5

ICA alleviates RSL3-induced oxidative damage. (A–C). Effects of ICA (5ug/ml) and Fer-1 (20 μM) on cell viability (A), cytotoxicity (B) and MDA levels (C) in KGN cells induced by RSL3 (300 nM). (D-G), ROS (D,E) and lipid oxidation levels (F,G) in KGN cells of different treatment groups were detected and quantified using DCFH-DA and C11-BODIPY 581/591 probes, respectively. Data are presented as mean ± SEM, ****P < 0.0001.

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