Figure 2 | Scientific Reports

Figure 2

From: Identification of differentially expressed tumour-related genes regulated by UHRF1-driven DNA methylation

Figure 2

Functional enrichment analysis of the DMGs. (A) Pie chart showing the DMR quantity and proportion of CG context, CHG context and CHH context that were identified. (B) The DMRs were annotated and anchored into promoters and gene bodies, including 488 and 1696 genes that were hypermethylated and hypomethylated in promoters and 1149 and 5501 genes that were hypermethylated and hypomethylated in gene bodies. (C–F) BP, CC, MF, and KEGG pathway enrichment analysis of the hypomethylated promoter or hypomethylated gene bodies. GO: Gene Ontology, BP: biological process, MF: molecular function, CC: cell component, KEGG: Kyoto Encyclopedia of Genes and Genomes. Significantly enriched biological processes were ranked by p value, and the top ten Gene Ontology terms are shown. For KEGG terms, the top twenty-five terms are shown. The size of the dots represents the number of enriched genes. The larger the dot is, the more genes are enriched.

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