Table 1 Hippocampal and cortical cytokine/chemokine changes after 3-weeks HA.
From: The role of microglia in neuronal and cognitive function during high altitude acclimatization
Region | Cytokine/Chemokine | SL | SL-PLX | HA | HA-PLX | Statistical outcome | P value | F (DFn, DFd) |
|---|---|---|---|---|---|---|---|---|
Average ± SEM | Average ± SEM | Average ± SEM | Average ± SEM | |||||
Hippocampus | MIP-1α | 3.65 ± 0.41 | 3.62 ± 0.44 | 3.47 ± 0.58 | 2.34 ± 0.25 | ns |  > 0.05 | F (1, 16) > 4.49 |
IL-15 | 25.82 ± 1.31 | 34.46 ± 3.30 | 34.52 ± 2.05 | 31.51 ± 2.49 | HA X Diet interaction | 0.0452 | F (1, 16) = 4.720 | |
IL-33 | 47.84 ± 4.42 | 85.22 ± 7.86 | 81.76 ± 2.89 | 75.80 ± 6.59 | Main effect of Diet | 0.0270 | F (1, 16) = 5.930 | |
HA X Diet interaction | 0.0040 | F (1, 16) = 11.29 | ||||||
IL-17A/F | 0.69 ± 0.01 | 0.95 ± 0.08 | 0.87 ± 0.03 | 0.94 ± 0.05 | Main effect of Diet | 0.0135 | F (1, 16) = 7.695 | |
Cortex | MIP-1α | 2.59 ± 0.09 | 5.02 ± 0.39 | 2.18 ± 0.09 | 3.81 ± 0.11 | Main effect of HA | 0.0042 | F (1, 16) = 11.10 |
Main effect of Diet |  < 0.0001 | F (1, 16) = 70.44 | ||||||
IL-15 | 23.82 ± 1.09 | 22.26 ± 1.66 | 26.59 ± 2.36 | 20.00 ± 2.32 | ns |  > 0.05 | F (1, 16) > 4.49 | |
IL-33 | 33.03 ± 2.23 | 37.82 ± 2.92 | 45.10 ± 2.62 | 36.55 ± 3.65 | HA X Diet interaction | 0.0352 | F (1, 16) = 5.29 | |
IL-17A/F | 0.562 ± 0.04 | 0.636 ± 0.04 | 0.768 ± 0.14 | 0.639 ± 0.04 | ns |  > 0.05 | F (1, 16) > 4.49 |
